My Travel Through Alzheimer's Disease #6 ROUND 2 + MRI info

MRI RESULTS

Below: Amyloid β (Aβ) is a fragment of the APP protein that, when it 
misfolds and clumps together, forms amyloid plaques, 
one of the main hallmarks of Alzheimer’s disease.

I had a brain MRI on July 7. What follows is a comparison of the brain MRI on January 23.

MR Brain WO IV Contrast

COMPARISON: 1/23/2025   

FINDINGS:   

·    Cerebrum: Normal signal intensity. No mass effect, midline shift, hemorrhage, or acute infarct.

·        

·    Cerebellum: Normal.

·    Brainstem: Normal.

·    Ventricles: No hydrocephalus.

·    Extraaxial spaces: Normal.

·        

·    Bones: No focal osseous lesion.

·    Visualized sinuses: Partial opacification of the mastoid air cells. Mucous retention cyst in the left maxillary sinus

·    Other: Normal intracranial intravascular flow voids.  

·        

IMPRESSION:

·     Stable examination. No acute intracranial process.

Thanks again for your concern and your prayers. 

I am blessed by your friendships.

CURRENT SCORE:

donanemab-azbt(Kisunla) - 2.5 💥 ALZEHIMER DISEASE - 0

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Amazon's Author's Page: http://tinyurl.com/CRD-Author
Facebook: https://www.facebook.com/CRDowningAurhor?ref=hl

My Blogs

Life as I see it: Topics range from general interest to lovers of life: authors, teachers, etc,

http://crdowning-aurhot.blogspot.com/?alt=rss

My Christian Context: Periodic posts on Christianity

http://my christiancontext.bloggspot.com/

Website: www.crdowing.com

My Travel Through Alzheimer's Disease #6 ROUND 2

ROUND 2 

 Yesterday, July 7, 2025, I had my second infusion of Kisunla. Specifically:

donanemab-azbt (Kisunla) 700 mg in sodium chloride 150 mL IVPB

Last given at 8:50 AM for Mild cognitive impairment (MCI) due to Alzheimer's disease.

Stopped at 9:20 AM for Mild cognitive impairment (MCI) 

Due to Alzheimer's disease sodium chloride 0.9% flush 10 mL 

I FEEL LIKE I HAVE LESS CONFUSION IN MY BRAIN THAN LAST WEEK.

THANKS FOR ALL YOUR SUPPORT AND PRAYERS.

NEXT POST WILL BE WHAT I FIND OUT FROM THE SCHEDULED BRAIN MRI.

Today went well. No glitches. The nurse was pleased to hear that I noticed substantial improvement in some areas.

Now, as I type this, I'm not hitting as many wrong keys as yesterday, so I'm changing the score and giving Kisunla another point. 

Check for an update on this Wednesday. I hope to the results of my MRI from last Monday.  

CURRENT SCORE:

donanemab-azbt (Kisunla) - 2 💥 ALZEHIMER DISEASE - 0

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Amazon's Author's Page: http://tinyurl.com/CRD-Author
Facebook: https://www.facebook.com/CRDowningAurhor?ref=hl

My Blogs

Life as I see it: Topics range from general interest to lovers of life: authors, teachers, etc,

http://crdowning-aurhot.blogspot.com/?alt=rss

My Christian Context: Periodic posts on Christianity

http://my christiancontext.bloggspot.com/

Website: www.crdowing.com

My Travel Through Alzheimer's Disease #8 ROUND 1

ROUND 1 

Yesterday, June 9, 2025, I had my first infusion of Kisunla. Specifically:

donanemab-azbt (Kisunla) 700 mg in sodium chloride 150 mL IVPB

Last given at 4:46 PM for Mild cognitive impairment (MCI) due to Alzheimer's disease.

Stopped at 5:15 PM for Mild cognitive impairment (MCI) 

Due to Alzheimer's disease sodium chloride 0.9% flush 10 mL 

I FEEL LIKE I HAVE LESS CONFUSION IN MY BRAIN THAN I HAD YESTERDAY MORNING.

THANS FOR ALL YOUR SUPPORT AND PRAYERS.

NEXT POST WILL BE WHAT I FIND OUT FROM THE SCHEDULED BRAIN MRI.

CURRENT SCORE:

donanemab-azbt (Kisunla) - 1 💥 ALZEHIMER DISEASE - 0

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Amazon's Author's Page: http://tinyurl.com/CRD-Author
Facebook: https://www.facebook.com/CRDowningAurhor?ref=hl

My Blogs

Life as I see it: Topics range from general interest to lovers of life: authors, teachers, etc,

http://crdowning-aurhot.blogspot.com/?alt=rss

My Christian Context: Periodic posts on Christianity

http://my christiancontext.bloggspot.com/

Website: www.crdowing.com

My Travel Through Alzheimer's Disease #7 My attack begins

MY ATTACK BEGINS! 

Today I made appointments for my infusions of PR INJ. DONANEMABAZBT, 2MG. I've been using the  name of Kisunla for the drug.

Treatments are once each month and are scheduled through December of 2025. Between each treatment is a brain MRI. If I understand why, the MRI's are to track the effectiveness of the treatment. 

If you want specifics...

https://kisunla.lilly.com/treatment#preparing-for-infusions

https://kisunla.lilly.com/patient-stories

Thank you for your concern and prayers.

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Amazon's Author's Page: http://tinyurl.com/CRD-Author
Facebook: https://www.facebook.com/CRDowningAurhor?ref=hl

My Blogs

Life as I see it: Topics range from general interest to lovers of life: authors, teachers, etc,

http://crdowning-aurhot.blogspot.com/?alt=rss

My Christian Context: Periodic posts on Christianity

http://my christiancontext.bloggspot.com/

Website: www.crdowing.com

Exploring My Updated Website - Part 3 - My Books (A)

 

https://www.crdowning.com/

Cover Photo by Damian Markutt on Unsplash

The TRAVELER'S HOT L Series

The original TRAVELER'S HOT L book contained eight short stories. It was a USA BEST BOOK AWARDS WINNER from the USABookNews.Com. The book was printed and sold by what the publisher called "CO-PUBLISHING." Since then the most common (and truthful) term is "VANITY PUBLISHING."

The total publicity I got from the publisher was to send me 10 copies of a very professional description of the book. That's all.

The author's name was wrong on the website, and no mention was made of the award.
Lesson learned: DO NOT SELF-(VANITY)- publish!  There are good independent publishers. There are also bad independent publishers.

I opted for KDP Publishing, part of the amazon mega family. Their service used to be more personal, but it still isn't bad. The have a strict policy on quality of writing. They also offer help with that. 

Amazon offers promotion packages. I have no experience with those.

Reality is, if you self/vanity/amazon publish, you won't get rich. There are many authors who make lots of money with amazon. But, there are more that don't.

Since I submitted TRAVELER'S HOT L, I've invested OVER TWENTY-THOUSAND DOLLARS in publishing. I've received a little over $1500 in royalties.

BUT I'M GOING TO KEEP WRITING.

A LOOK AT THE TRAVELER'S HOT L SERIES BOOKS ONE BY-BY-ONE.

THE TIME TRAVELER'S RESORT

TRAVELER'S HOT L - VOLUME 2

I can't type TRAVELER'S HOT L - VOLUME 3's title. You'll see why below.

This book is written the spirit of Alice's Adventures in Wonderland, but with a twist by an evil entity known by many names. 

Talking, directions, and time all backwards in this antiparallel world.

Tempus, one of the keepers of life-strings in, is trapped in that space and must return to her real time and must convince those trapped there must "look now to the heavens." 

In the end, the name of the entity holding the group in the is revealed, and is not happy by that. 

 

 

Next Website Post: My Books (B)

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Amazon's Author's Page: http://tinyurl.com/CRD-Author
Facebook: https://www.facebook.com/CRDowningAurhor?ref=hl

My Blogs

Life as I see it: Topics range from general interest to lovers of life: authors, teachers, etc,

http://crdowning-aurhot.blogspot.com/?alt=rss

My Christian Context: Periodic posts on Christianity

http://my christiancontext.bloggspot.com/

Website: www.crdowing.com

Exploring My Updated Website - Part 2

 

https://www.crdowning.com/

Cover Photo by Damian Markutt on Unsplash

Part 1 of this series was an overview of the new website. 

This week I'll focus on ME. 😇

• About - the first section

Dr. Downing received several awards for his teaching. He was a "San Diego County Teacher of the Year," won the CIBA-GEIGY Award for Excellence in Science Teaching from NSTA, was a Christa McAuliffe Fellow in 1992.

In 1993, he won the prestigious Presidential Award for Excellence in Science Teaching.

Outside the classroom,Dr. Downing is a developer of curricula with six lab/activities marketed by Science Kit and Ward's Biological Supply. He's also authored three books of laboratory and creative activities that promote critical thinking and authored and edited a four-volume set of textbooks (Making Connections: Integrating the Science of 1) Water; 2) The Atmosphere; 3) The Human Body; 4) Energy) for a thematic-integrated science program. Each text was one semester of coursework.

• Betrayal in Blue  -  several short pre-publication reviews
• Book Reviews  - Betrayal in Blue's booklife review and Paul Wandson Blog: Time-To-Time-Travel's 5-star review of Pattern's on Pages.

From here on is not in the Website. 

Publisher's Weekly's review below is another review of Betrayal in Blue, by far the longest book I've written. It's thorough and said it was 

"Great for fans of JOSEPH WAMBAUGH and ED MCBAIN."

Next Website Post: My Books (A)

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Amazon's Author's Page: http://tinyurl.com/CRD-Author
Facebook: https://www.facebook.com/CRDowningAurhor?ref=hl

My Blogs

Life as I see it: Topics range from general interest to lovers of life: authors, teachers, etc,

http://crdowning-aurhot.blogspot.com/?alt=rss

My Christian Context: Periodic posts on Christianity

http://my christiancontext.bloggspot.com/

Website: www.crdowing.com

Exploring My Updated Website - Part 1

https://www.crdowning.com/

Cover Photo by Damian Markutt on Unsplash

My website was designed to showcase my writing. 

It worked out that way, but had too much "clever" pieces of writing and too few showcase pieces.

I think I've fixed it.

This first week of the exploration is an overview of the fixes. 

The photograph at the top of each post in the series was FREE on Unsplash. They ask that you give credit to the photographer. Although that's not mandatory, I always do it.

It all started in June of 2012 . . .

I retired from full-time teaching and decided to become a writer.

Since then I've authored a total of 20 books in five genres:

Science Fiction: The Traveler’s HOT L series - 6 books; INSECTICIDE; We Are The Observers; and Classics Malt Shop

Police Fiction: BETRAYAL IN BLUE - the story takes place 1980's

Miscellaneous Genres: Sir Isaac's Car (humor for all ages); Writing: Idea Farming and Book Creation

Medical Information: NICU - An Insider’s Guide

Christianity: Biblical Fiction: Who Leads the Shepherd?;

EXPRESSIONS OF FAITH Bible Studies: Hebrews & Acts

Action/Spy/Thriller: The Antidote Conspiracy - Book 1 of the Glitter & Leroy series

I co-authored a book for teachers of all ages:

TUNE UP YOUR TEACHING & TURN ON STUDENT LEARNING

I was a contributor to three books.

Science Fiction: Drop by Drop in MIND SCAPES UNIMAGINED and What Goes Around in A WORLD UNIMAGINED

Non Fiction: Let "You" Show Through inThe Making of a Presidential Mathematics and Science Educator

If you haven't read any of them, 😟.

If you haven't read all of them, 

You can fix that 😉.

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Amazon's Author's Page: http://tinyurl.com/CRD-Author
Facebook: https://www.facebook.com/CRDowningAurhor?ref=hl

My Blogs

Life as I see it: Topics range from general interest to lovers of life: authors, teachers, etc,

http://crdowning-aurhot.blogspot.com/?alt=rss

My Christian Context: Periodic posts on Christianity

http://my christiancontext.bloggspot.com/

Website: www.crdowing.com